Alpha 2-antiplasmin Chr. Chromosome 17 (human)[1] UniProt P08697 Location (UCSC) Chr 17: 1.74 – 1.76 Mb Available structuresPDBList of PDB id codes Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes2R9Y List of PDB id codes List of PDB id codes2R9Y PubMed search [2] RefSeq (protein) NP_000925NP_001159392NP_001159393 Aliases SERPINF2, A2AP, AAP, ALPHA-2-PI, API, PLI, serpin family F member 2 RefSeq (mRNA) NM_000934NM_001165920NM_001165921 PDB Human UniProt search: PDBe RCSB Gene ontologyMolecular functionCellular componentBiological process Gene ontologyMolecular function• peptidase inhibitor activity• protein homodimerization activity• protease binding• GO:0001948 การจับกับโปรตีน• serine-type endopeptidase inhibitor activity• endopeptidase inhibitor activityCellular component• blood microparticle• ไฟบริโนเจน• extracellular region• cell surface• เอกโซโซมชนิดภายนอกเซลล์• platelet alpha granule lumen• ภายนอกเซลล์• สารเคลือบเซลล์ที่มีคอลลาเจนเป็นส่วนประกอบBiological process• positive regulation of collagen biosynthetic process• negative regulation of peptidase activity• negative regulation of fibrinolysis• negative regulation of plasminogen activation• regulation of blood vessel diameter by renin-angiotensin• blood vessel morphogenesis• fibrinolysis• collagen fibril organization• platelet degranulation• positive regulation of JNK cascade• response to organic substance• acute-phase response• positive regulation of cell differentiation• positive regulation of ERK1 and ERK2 cascade• positive regulation of transforming growth factor beta production• positive regulation of stress fiber assembly• positive regulation of transcription from RNA polymerase II promoter• positive regulation of smooth muscle cell proliferation• positive regulation of cell-cell adhesion mediated by cadherin• negative regulation of endopeptidase activitySources:Amigo / QuickGO Cellular component • blood microparticle• ไฟบริโนเจน• extracellular region• cell surface• เอกโซโซมชนิดภายนอกเซลล์• platelet alpha granule lumen• ภายนอกเซลล์• สารเคลือบเซลล์ที่มีคอลลาเจนเป็นส่วนประกอบ External IDs OMIM: 613168 HomoloGene: 719 GeneCards: SERPINF2 End 1,755,268 bp[1] Ensembl ENSG00000167711ENSG00000276838 Molecular function • peptidase inhibitor activity• protein homodimerization activity• protease binding• GO:0001948 การจับกับโปรตีน• serine-type endopeptidase inhibitor activity• endopeptidase inhibitor activity BandStart 17p13.3 Gene location (Human)Chr.BandStartEnd Gene location (Human)Chr.Chromosome 17 (human)[1]Band17p13.3Start1,742,836 bp[1]End1,755,268 bp[1] RNA expression pattern RNA expression patternMore reference expression data Biological process • positive regulation of collagen biosynthetic process• negative regulation of peptidase activity• negative regulation of fibrinolysis• negative regulation of plasminogen activation• regulation of blood vessel diameter by renin-angiotensin• blood vessel morphogenesis• fibrinolysis• collagen fibril organization• platelet degranulation• positive regulation of JNK cascade• response to organic substance• acute-phase response• positive regulation of cell differentiation• positive regulation of ERK1 and ERK2 cascade• positive regulation of transforming growth factor beta production• positive regulation of stress fiber assembly• positive regulation of transcription from RNA polymerase II promoter• positive regulation of smooth muscle cell proliferation• positive regulation of cell-cell adhesion mediated by cadherin• negative regulation of endopeptidase activity Species Human Entrez 5345
ใกล้เคียง Alpha Alpha-thalassemia Alpha motoneuron Alpha-1 antitrypsin Alphabet Inc. Alpha-Linolenic acid Alpha lactalbumin Alpha Centauri Alpha 2-antiplasmin Alpha Condé
